Table 2:
Patient Demographics and Clinical Characteristics
| iMCD Total n=63 |
iMCD-TAFRO n=38 |
iMCD-IPL n=11 |
iMCD-NOS n=14 |
p-value‡ | |
|---|---|---|---|---|---|
| Gender, n (%) | |||||
| Male | 34 (54) | 22 (58) | 4 (36) | 8 (57) | 0.492 |
| Female | 29 (46) | 16 (42) | 7 (64) | 6 (43) | |
| Age at diagnosis | |||||
| Mean (SD) | 35.6 (16) | 33.6 (18) | 42.5 (10) | 35.5 (14) | 0.294 |
| Self-reported race, n (%) | |||||
| Black | 7 (11) | 3 (8) | 0 | 4 (29) | 0.0183 |
| White | 39 (62) | 27 (71) | 4 (36) | 8 (57) | |
| Asian | 9 (14) | 3 (8) | 5 (46) | 1 (7) | |
| Other | 8 (13) | 5 (13) | 2 (18) | 1 (7) | |
| Histopathological subtype, n (%) | |||||
| Hypervascular | 39 (62) | 29 (76) | 1 (9) | 9 (64) | <0.0001 |
| Mixed | 16 (25) | 9 (24) | 3 (27) | 4 (29) | |
| Plasmacytic | 5 (8) | 0 | 5 (46) | 0 | |
| Unknown | 3 (5) | 0 | 2 (18) | 1 (7) | |
| Constitutional symptoms, n (%) | |||||
| Yes | 60 (95) | 37 (97) | 10 (91) | 13 (93) | 0.345 |
| No | 3 (5) | 1 (3) | 1 (9) | 1 (7) | |
| Not assessed | 0 | 0 | 0 | 0 | |
| Organomegaly, n (%) | |||||
| Yes | 49 (79) | 35 (92) | 4 (36) | 10 (77) | 0.0005 |
| No | 13 (21) | 3 (8) | 7 (64) | 3 (23) | |
| Not assessed | 1 | 0 | 0 | 1 | |
| Fluid accumulation, n (%) | |||||
| Yes | 51 (86) | 38 (100) | 5 (56) | 8 (67) | 0.0001 |
| No | 8 (14) | 0 | 4 (44) | 4 (33) | |
| Not assessed | 4 | 0 | 2 | 2 |
‡
p-values were generated from Fisher’s exact analysis of iMCD-TAFRO, iMCD-IPL, and iMCD-NOS.