Table 3:
Laboratory values across iMCD subtypes
| Normal Range | iMCD Total | iMCD-TAFRO | iMCD-IPL | iMCD-NOS | p-value‡ | |
|---|---|---|---|---|---|---|
|
White blood cells (109/L) Mean (SD), n |
4.5 – 11.0 | 10.9 (5.8), 63 | 12.3 (6.4), 38 | 7.83 (3.3), 11 | 9.50 (4.7), 14 | 0.0460 |
|
Absolute neutrophils (109/L) Mean (SD), n |
1.8 – 7.7 | 6.9 (3.9), 60 | 7.43 (3.9), 35 | 5.52 (3.5), 11 | 6.41 (4.1), 14 | 0.331 |
|
Absolute lymphocytes (109/L) Mean (SD), n |
1.0 – 4.8 | 1.80 (1.1), 58 | 1.85 (1.2), 35 | 1.31 (0.4), 10 | 2.23 (1.0), 13 | 0.131 |
|
Absolute monocytes (109/L) Mean (SD), n |
0.2 – 1.2 | 0.73 (0.6), 59 | 0.79 (0.6), 35 | 0.63 (0.4), 10 | 0.63 (0.5), 14 | 0.551 |
|
Absolute eosinophils (109/L) Mean (SD), n |
0.0 – 0.9 | 0.10 (0.1), 57 | 0.08 (0.1), 33 | 0.11 (0.1), 10 | 0.15 (0.1), 14 | 0.0965 |
|
Absolute basophils (109/L) Mean (SD), n |
0.0 – 0.3 | 0.03 (0.1), 56 | 0.04 (0.1), 34 | 0.04 (0.1), 9 | 0.02 (0.02), 13 | 0.776 |
|
Platelets (109/L) Mean (SD), n |
150 – 400 | 212 (173), 61 | 123 (100), 36 | 440 (200), 11 | 271 (107), 14 | <0.0001 |
|
MPV (fL) Mean (SD), n |
6.0 – 13.2 | 9.64 (2.1), 60 | 10.3 (1.8), 38 | 7.65 (1.5), 10 | 9.09 (2.2), 12 | 0.0019 |
|
Hemoglobin (g/dL) Mean (SD), n |
13.5 – 17.5 | 10.2 (2), 63 | 9.7 (2), 38 | 10.3 (3), 11 | 11.5 (2), 14 | 0.0385 |
|
CRP (mg/L) Mean (SD), n |
> 10 | 99.3 (93), 48 | 111 (101), 33 | 112 (68), 8 | 31.0 (39), 7 | 0.107 |
|
Albumin (g/dL) Mean (SD), n |
3.5 – 5.5 | 2.7 (1), 62 | 2.4 (1), 38 | 2.9 (1), 11 | 3.6 (1), 13 | <0.0001 |
|
Creatinine (mg/dL) Mean (SD), n |
0.6 – 1.3 | 1.2 (1), 62 | 1.3 (1), 38 | 0.8 (0.3), 11 | 1.2 (1), 13 | 0.129 |
|
IgG (mg/dL) Mean (SD), n |
600 – 1700 | 1,989 (1,758), 51 | 1,254 (927), 32 | 4,773 (1,728), 10 | 1,504 (716), 9 | <0.0001 |
‡
p-values were generated from one-way ANOVA analysis of iMCD-TAFRO, iMCD-IPL, and iMCD-NOS.