Table 4.
Performance of DAST compared with reference AST method for GPC by VITEK-2 System
Organisms and antibiotic tested (n × Ab = N) | Categorical agreement, n (%) | Categorical disagreement, n (%) among isolate-antibiotic combinations tested | Essential agreement | ||||
---|---|---|---|---|---|---|---|
Minor error | Major error | Very major error | Total | Agreed | Disagreed | ||
Staphylococcus spp. (49 × 15 = 735) | 729 (99.2%) | 3 (0.4%) | 2 (0.27%) | 1 (0.13%) | 6 (0.8%) | 732 (99.6%) | 03 (0.4%) |
Enterococcus spp. (16 × 15 = 240) | 238 (99.2%) | 0 (0.0%) | 2 (0.8%) | 0 (0.0%) | 2 (0.8%) | 238 (99.2%) | 02 (0.8%) |
Antibiotics tested (N = 65) | Categorical agreement, n (%) | Categorical disagreement (%) | Essential agreement | ||||
Minor error | Major error | Very major error | Total | Agreed | Disagreed | ||
Benzyl penicillin | 65 (100.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 65 (100.0%) | 0 (0.0%) |
Tetracycline | 65 (100.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 65 (100.0%) | 0 (0.0%) |
Teicoplanin | 60 (92.3%) | 3 (4.6%) | 2 (3.1%) | 0 (0.0%) | 5 (7.7%) | 63 (96.9%) | 2 (3.1%) |
Vancomycin | 58 (89.2%) | 3 (4.6%) | 4 (6.2%) | 0 (0.0%) | 7 (10.8%) | 62 (95.4%) | 3 (4.6%) |
Erythromycin | 63 (96.9%) | 0 (0.0%) | 2 (3.1%) | 0 (0.0%) | 2 (3.1%) | 65 (100.0%) | 0 (0.0%) |
Clindamycin | 64 (98.5%) | 0 (0.0%) | 1 (1.5%) | 0 (0.0%) | 1 (1.5%) | 65 (100.0%) | 0 (0.0%) |
Linezolid | 65 (100.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 65 (100.0%) | 0 (0.0%) |
Levofloxacin | 62 (95.4%) | 3 (4.6%) | 0 (0.0%) | 0 (0.0%) | 3 (4.6%) | 64 (98.5%) | 1 (1.5%) |
Ciprofloxacin | 62 (95.4%) | 3 (4.6%) | 0 (0.0%) | 0 (0.0%) | 3 (4.6%) | 64 (98.5%) | 1 (1.5%) |
Cotrimoxazole | 63 (96.9%) | 0 (0.0%) | 2 (3.1%) | 0 (0.0%) | 2 (3.1%) | 65 (100.0%) | 0 (0.0%) |