Table 1.
Baseline patient characteristics by glycemic variability quartiles
|
Quartile 1
≤19% |
Quartile 2
20–27% |
Quartile 3
28–34% |
Quartile 4
≥35% |
p | |
|---|---|---|---|---|---|
| Number of patients, n (%) | 56 (23) | 63 (26) | 59 (25) | 61 (26) | – |
| Age, median (IQR) | 48 (37–65)a | 62 (48–74)a | 59 (53–68)a | 64 (56–67)a | <0.001* |
| Gender | 0.69 | ||||
| Female, n (%) | 28 (50) | 27 (42) | 23 (39) | 27 (44) | |
| Male, n (%) | 28 (50) | 36 (58) | 36 (61) | 34 (56) | |
| DM, n (%) | 3 (5)a | 9 (14)b | 24 (41)ab | 30 (49)ab | <0.001* |
| Number of comorbidities | <0.001* | ||||
| 0, n (%) | 26 (46) | 21 (33) | 7 (12) | 10 (10) | |
| 1–3, n (%) | 28 (50) | 33 (52) | 45 (76) | 31 (51) | |
| ≥3, n (%) | 2 (4) | 9 (15) | 7 (12) | 20 (39) | |
| BMI, median (IQR)† | 30 (26–38) | 29 (25–35) | 33 (27–34) | 31 (25–37) | 0.69 |
| Obesity, n (%)† | 28 (50) | 30 (48) | 29 (49) | 32 (52) | 0.86 |
| SAPS-3, median (IQR) | 52 (43–62)a | 59 (50–68) | 57 (48–67) | 63 (52–70)a | 0.007* |
| SOFA, median (IQR) | 3 (3–6)a | 5 (3–6) | 6 (3–7)a | 4 (4–8)a | 0.002* |
| MV, n (%) | 36 (64)a | 55 (87)a | 50 (84) | 55 (90)a | 0.001* |
BMI, body mass index; DM, diabetes mellitus; IQR, interquartile range; MV, mechanical ventilation; SAPS-3, simplified acute physiology score 3; SOFA, sequential organ failure assessment. *p < 0.05 is considered statistically significant. Continuous and ordinal variables were compared using the Kruskal–Wallis test, with Dwass–Steel–Critchlow–Fligner multiple comparisons test. Categorical variables compared using the Chi-square test. aStatistically significant difference between quartile 1 compared to other quartiles. bStatistically significant difference between quartile 2 compared to other quartiles. †BMI information was not obtained for 6 patients in quartile 1, 2 patients in quartile 2, 4 patients in quartile 3, and 4 patients in quartile 4