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. 2024 Apr 2;19:3123–3142. doi: 10.2147/IJN.S437714

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© 2024 Twamley et al.

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Laminar shear stress stimulation altered the expression of extra cellular matrix components. (A) Heat map shows statistically significant differentially expressed ECM genes at >8% false discovery rate (FDR) from each S- and LSS-cultivated HUVEC. ECM genes of particular interest are highlighted. (B) Volcano plot depicts the q-value over the log₂ fold change between the LSS-cultivated HUVEC group and the S-cultivated HUVEC group. Data analyzed by a paired t-test using a multiple comparisons false discovery rate (FDR) with a two-stage step-up (Benjamini, Krieger, and Yekutieli) method, q < 0.08. n = 5.