Table 5.

Unadjusted and multivariable analyses of predictors of survival in the all-comers cohort (n = 82).

Predictor	Hazard ratio (95% CI)	P-value
Unadjusted analysis
Age (per y)	1.06 (1.00–1.12)	.048
Female (vs male)	2.06 (0.89–4.78)	.09
Etiology of liver disease
NAFLD (vs hepatitis C)	2.44 (0.94–6.33)	.07
Alcohol (vs hepatitis C)	2.05 (0.70–6.03)	.19
Other including hepatitis B or > 1	1.39 (0.47–4.07)	.55
diagnosis (vs hepatitis C)
MELD score (per point)	1.07 (0.97–1.18)	.18
Child’s B/C cirrhosis (vs A)	3.01 (1.40–6.47)	.005
AFP (ng/mL)
≥ 20 (vs < 20)	0.74 (0.35–1.59)	.44
≥ 100 (vs < 100)	1.31 (0.59–2.89)	.51
≥ 500 (vs < 500)	2.40 (0.96–5.99)	.06
≥ 1000 (vs < 1000)	4.89 (1.82–13.18)	.002
Total tumor burden (per cm)	1.02 (0.90–1.16)	.72
Number of lesions + largest lesion diameter (per unit)	0.90 (0.75–1.08)	.26
Number of HCC lesions	0.86 (0.70–1.06)	.15
Systemic therapy (vs none)	1.43 (0.49–4.13)	.51
Multivariable analysis
Etiology of liver disease: NAFLD (vs hepatitis C)	2.77 (1.05–7.29)	.04
AFP ≥ 500 (vs < 500)	3.50 (1.27–9.65)	.02
Child’s B/C cirrhosis (vs A)	3.35 (1.39–8.11)	.007

Abbreviations: AFP, alpha-fetoprotein; CI, confidence interval; HCC, hepatocellular carcinoma; MELD, Model for End-Stage Liver Disease; NAFLD, nonalcoholic fatty liver disease.