VIP Scores represent whether a given input variable is an important
predictor in the PLSR model (across all components). Variables with a VIP score
> 1 (highlighted by the black horizontal line at VIP value = 1) are
considered important to the PLS model’s prediction. A) VIP scores for all
variables entered in the episodic memory model. B) VIP scores for all variables
entered in the executive function model. BDNF, brain-derived neurotrophic
factor; BMI, body mass index; BP, blood pressure; CSF, cerebrospinal fluid;
HB-EGF-like-GF, heparin-binding epidermal growth factor like-growth factor;
IL-6, interleukin-6; IGF, insulin-like growth factor; p-tau, phosphorylated
tau181; t-tau, total tau; VEGF, vascular endothelial growth
factor.