Table 1.

Interpretation of different parameters obtained from 3D-mode US-PAI

Parameter	Units	Data interpretation	Biological meaning
Volume	mm3	Tumor volume	Tumor volume
sO2 Average 3D	%	Average ratio of HbO2 to Hb only including voxels above the HbT threshold	Oxygenation level in the tumor vasculature
sO2 Average Total 3D	%	Average ratio of HbO2 to Hb without applying HbT threshold	Oxygenation level in the whole tumor mass
HbT Average 3D	arbitrary units	Average HbT level per voxel in the tumor	Blood flow normalized to tumor size
HbT 3D	arbitrary units	Total HbT level in the tumor	Total blood flow in the tumor