Fig. 4. Toxicity of Le in vivo. (A) Survival curves of mice orally administered Le at a single dose of 0, 4, 20, 100, 500, or 2500 mg kg−1 body weight for 14 days. The subchronic toxicity evaluation of oral Le with a single dose of 0, 4, 20, 100, 500, or 2500 mg kg−1 in mice. (B) Detection of food intake and plotting of food intake change curves. (C) Body weight was monitored and plotted for body weight changes. Mice were killed on day 14 and assayed for (D) RBCs, (E) WBCs, and (F) PLTs.
