Table 2.
Demographic and laboratory findings of the enrolled patients. The age and sex profile of the control group are also given in the table. The statistical values are calculated using the Fisher's exact test.
| Variable | Moderate Patients | Severe Patients | P-value | Control group |
|---|---|---|---|---|
| Gender | ||||
| Male, N (%) | 36 (63.2%) | 32 (61.5%) | 0.862 | 39 (55.7%) |
| Female, N (%) | 21(36.8%) | 20 (38.5%) | 31 (44.3%) | |
| Total, N (%) | 57 (52.3%) | 52 (47.7%) | 70 | |
| Age | ||||
| <40 | 11 (19.3%) | 5 (9.6%) | 0.269 | 37 (52.8%) |
| 40–60 | 16 (28.1%) | 20 (38.5%) | 33 (47.2%) | |
| >60 | 30 (52.6%) | 27 (51.9%) | ||
| Laboratory Findings (mean ± SD) | P-value | ||
|---|---|---|---|
| RR (bpm) | 25.03 ± 4.99 | 29.88 ± 5.78 | < 0.001** |
| PR (bpm) | 84.21 ± 11.13 | 88.73 ± 13.39 | 0.054 |
| O2 saturation (%) | 94.84 ± 6.80 | 86.06 ± 11.90 | < 0.001** |
| ESR (mm/hr) | 45.90 ± 23.74 | 62.42 ± 31.50 | 0.004** |
| Cr (mg/dL) | 1.65 ± 1.86 | 1.66 ± 1.26 | 0.982 |
| AST (U/L) | 41.21 ± 21.82 | 75.78 ± 74.89 | 0.003** |
| BUN (mg/dL) | 24.57 ± 23.10 | 36.08 ± 30.86 | 0.035* |
| ALT (U/L) | 30.89 ± 26.79 | 48.48 ± 51.79 | 0.038* |
| ALP (U/L) | 198.19 ± 86.19 | 215.89 ± 103.64 | 0.351 |
| Alb (g/dL) | 4.05 ± 0.74 | 4.10 ± 0.57 | 0.671 |
| CRP (mg/L) | 40.1 ± 18.9 | 49.2 ± 21.3 | 0.018* |
| LDH (U/L) | 567.5 ± 229.1 | 802.4 ± 407.4 | < 0.001** |
| D-dimer (ng/ml) | 564.1 ± 265.8 | 896.6 ± 476.3 | < 0.001** |
Data are presented as mean ± SD or the frequency of individuals (percentage). According to the calculated values, levels of AST, BUN, ALT, CRP, LDH, ESR, O2 saturation, respiratory rate and D-dimer are significantly different in severe patients as compared with moderates due to the severity of disease. Abbreviations. RR: Respiratory rate. PR: Pulse rate. ESR: Erythrocyte sedimentation rate. Cr: Creatinine. AST: Aspartate aminotransferase. ALT: Alanine aminotransferase. BUN: Blood urea nitrogen. ALP: Alkaline phosphatase. Alb: Albumin. CRP: C-reactive protein. LDH: Lactate dehydrogenase. D-dimer: Fibrine degradation products (FDP).