Table 3.
Effect of methanolic extract of leaf of C. fistula L. on castor oil (1mL/mice) induced diarrhea in mice.
| Group | Treatment | Number of diarrheal feces (Average ± SEM) | % Reduction of Diarrhea | Significance Vs Control | Significance Vs Std |
|---|---|---|---|---|---|
| Group I | Control | 12.5 ± 0.29 | |||
| Group II | Standard | 2.5 ± 0.87** | 80 | 0.003 | |
| Group III | MESF (200 mg/kg) | 4.75 ± 0.75** | 62 | 0.002 | 0.062 |
| Group IV | MESF (400 mg/kg) | 3.5 ± 0.65** | 72 | 0.001 | 0.423 |
| Group V | MESF (600 mg/kg) | 3.75 ± 1.18** | 70 | 0.004 | 0.579 |
** and * respectively indicate that, the significant p value is less than 0.01 and 0.05 while comparing against control. Number of diarrheal feces represented as Average ± Standard Error of Mean (n = 4), Group I as control group, given 1% Tween 80 in normal saline at a 10 mL/kg body weight dose, Group II (Standard drug loperamide) at 10 mg/kg body weight dose, Group III (MESF 200 = Methanol Soluble Fraction at 200 mg/kg body weight dose); Group IV (MESF 400 = Methanol Soluble Fraction at 400 mg/kg bw dose) and Group V (MESF 600 = Methanol Soluble Fraction at 600 mg/kg body weight dose).