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. 2024 Mar 27;10(7):e28460. doi: 10.1016/j.heliyon.2024.e28460

Table 3.

Effect of methanolic extract of leaf of C. fistula L. on castor oil (1mL/mice) induced diarrhea in mice.

Group Treatment Number of diarrheal feces (Average ± SEM) % Reduction of Diarrhea Significance Vs Control Significance Vs Std
Group I Control 12.5 ± 0.29
Group II Standard 2.5 ± 0.87** 80 0.003
Group III MESF (200 mg/kg) 4.75 ± 0.75** 62 0.002 0.062
Group IV MESF (400 mg/kg) 3.5 ± 0.65** 72 0.001 0.423
Group V MESF (600 mg/kg) 3.75 ± 1.18** 70 0.004 0.579

** and * respectively indicate that, the significant p value is less than 0.01 and 0.05 while comparing against control. Number of diarrheal feces represented as Average ± Standard Error of Mean (n = 4), Group I as control group, given 1% Tween 80 in normal saline at a 10 mL/kg body weight dose, Group II (Standard drug loperamide) at 10 mg/kg body weight dose, Group III (MESF 200 = Methanol Soluble Fraction at 200 mg/kg body weight dose); Group IV (MESF 400 = Methanol Soluble Fraction at 400 mg/kg bw dose) and Group V (MESF 600 = Methanol Soluble Fraction at 600 mg/kg body weight dose).