Table 5.
Central analgesic effect of methanolic extract of C. fistula.
| Group | Treatment | Average time of tail immersion of Mice Time in Sec after Loading the Plant Sample/Drug |
||
|---|---|---|---|---|
| 30 min | 60 min | 90 min | ||
| Group I | Control | 2.158 ±.0834 | 2.15 ±.03894 | 2.68 ± 0.10638 |
| Group II | Standard | 5.293 ± 0.0825** | 10.018 ±.2732** | 15.64 ± 0.241** |
| Group III | MESF (200 mg/kg) | 2.995 ±.0924* | 4.268 ±.0423** | 5.403 ± 0.14505** |
| Group IV | MESF (400 mg/kg) | 3.873 ±.0727** | 4.938 ±.0909** | 6.345 ±.06614** |
| Group V | MESF (600 mg/kg) | 4.158 ±.1725** | 5.465 ±.31,415** | 7.61 ± 0.18918** |
**and * respectively indicate that, the significant p value is less than 0.01 and 0.05 while comparing against control; data indicated as average ± Standard Error of Mean (n = 4). Group I as control group, given 1% Tween 80 in normal saline at a 10 mL/kg body weight dose, Group II (Standard drug morphine 2 mg/kg), Group III (MESF 200 = Methanol Soluble Fraction at 200 mg/kg body weight dose); Group IV (MESF 400 = Methanol Soluble Fraction at 400 mg/kg bw dose) and Group V (MESF 600 = Methanol Soluble Fraction at 600 mg/kg body weight dose).