Skip to main content
. 2024 Mar 27;10(7):e28460. doi: 10.1016/j.heliyon.2024.e28460

Table 5.

Central analgesic effect of methanolic extract of C. fistula.

Group Treatment Average time of tail immersion of Mice Time in Sec after Loading the Plant Sample/Drug
30 min 60 min 90 min
Group I Control 2.158 ±.0834 2.15 ±.03894 2.68 ± 0.10638
Group II Standard 5.293 ± 0.0825** 10.018 ±.2732** 15.64 ± 0.241**
Group III MESF (200 mg/kg) 2.995 ±.0924* 4.268 ±.0423** 5.403 ± 0.14505**
Group IV MESF (400 mg/kg) 3.873 ±.0727** 4.938 ±.0909** 6.345 ±.06614**
Group V MESF (600 mg/kg) 4.158 ±.1725** 5.465 ±.31,415** 7.61 ± 0.18918**

**and * respectively indicate that, the significant p value is less than 0.01 and 0.05 while comparing against control; data indicated as average ± Standard Error of Mean (n = 4). Group I as control group, given 1% Tween 80 in normal saline at a 10 mL/kg body weight dose, Group II (Standard drug morphine 2 mg/kg), Group III (MESF 200 = Methanol Soluble Fraction at 200 mg/kg body weight dose); Group IV (MESF 400 = Methanol Soluble Fraction at 400 mg/kg bw dose) and Group V (MESF 600 = Methanol Soluble Fraction at 600 mg/kg body weight dose).