TABLE 1.
Variable | Singleton birth | Twin birth | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Autologous eggs | Donor eggs | Autologous eggs | Donor eggs | |||||||||
Fresh (n = 7,453) |
Cryopreserved (n = 1,052) |
P value | Fresh (n = 643) |
Cryopreserved (n = 269) |
P value | Fresh (n = 5,196) |
Cryopreserved (n = 540) |
P value | Fresh (n = 684) |
Cryopreserved (n = 100) |
P value | |
Age (y), mean ± SD | 35.28 ± 4.08 | 35.01 ± 3.88 | .04 | 41.78 ± 4.35 | 42.00 ± 5.04 | .53 | 34.51 ± 3.91 | 34.61 ± 3.90 | .58 | 41.08 ± 4.73 | 42.72 ± 4.26 | .001 |
Gravida ≥1, % | 53.70 | 32.89 | <.0001 | 54.90 | 33.83 | <.0001 | 28.43 | 22.96 | .009 | 27.92 | 16.00 | .01 |
Parity 0, % | 64.62 | 41.06 | <.0001 | 69.83 | 45.72 | <.0001 | 33.64 | 27.22 | .003 | 34.80 | 21.00 | .001 |
BMI (kg/m2), % | ||||||||||||
<18.5 | 1.02 | 0.95 | NA | 0.62 | 0.37 | NA | 1.33 | 0.74 | NA | 0.88 | 2.00 | NA |
18.5–24.9 | 24.37 | 18.44 | 23.17 | 20.07 | 24.25 | 23.52 | 19.44 | 18.00 | ||||
25–25.9 | 8.96 | 9.32 | 7.31 | 10.78 | 8.18 | 7.22 | 7.31 | 6.00 | ||||
>30 | 6.24 | 5.70 | 4.67 | 2.97 | 6.62 | 5.19 | 2.63 | 4.00 | ||||
Missing | 59.41 | 65.59 | 64.23 | 65.80 | 59.62 | 63.33 | 69.74 | 70.00 | ||||
Race/ethnicity, % | ||||||||||||
White | 84.74 | 84.32 | .22 | 87.09 | 90.71 | .52 | 85.16 | 82.96 | <.0001 | 91.52 | 78.00 | <.0001 |
Black | 3.02 | 4.18 | 2.18 | 2.60 | 2.52 | 5.56 | 2.05 | 6.00 | ||||
Hispanic | 3.37 | 3.61 | 3.42 | 2.60 | 3.87 | 5.56 | 1.46 | 2.00 | ||||
Native American | 1.05 | 0.67 | 0.78 | 0.37 | 1.23 | 1.30 | 0.88 | 0.00 | ||||
Asian/Pacific Islander | 7.74 | 7.22 | 6.07 | 3.72 | 7.10 | 4.26 | 3.51 | 14.00 | ||||
Unknown | 0.08 | 0.00 | 0.47 | 0.00 | 0.12 | 0.37 | 0.58 | 0.00 | ||||
Chronic hypertension, % | 1.27 | 2.00 | .06 | 2.80 | 1.86 | .49 | 1.66 | 1.11 | .47 | 4.39 | 4.00 | 1.00 |
Pregestational diabetes, % | 0.97 | 0.95 | .96 | 0.62 | 1.49 | .20 | 0.81 | 0.37 | .43 | 0.58 | 2.00 | .17 |
Infertility diagnosis, % | ||||||||||||
Tubal | 8.24 | 8.65 | .0004 | 0.93 | 1.86 | .0003 | 6.97 | 10.93 | .003 | 0.58 | 2.00 | .10 |
Ovulation | 8.06 | 9.22 | 2.33 | 7.43 | 9.16 | 10.74 | 4.39 | 8.00 | ||||
Diminished ovarian reserve | 3.74 | 0.95 | 41.68 | 31.97 | 3.23 | 1.11 | 39.47 | 26.00 | ||||
Endometriosis | 4.33 | 4.09 | 1.24 | 0.74 | 4.35 | 4.07 | 2.05 | 2.00 | ||||
Uterine | 0.99 | 1.33 | 0.31 | 1.12 | 1.12 | 0.93 | 0.29 | 0.00 | ||||
Male only | 24.47 | 24.52 | 1.87 | 0.74 | 23.60 | 25.17 | 4.68 | 4.00 | ||||
Other | 10.08 | 8.75 | 19.44 | 28.25 | 9.45 | 10.74 | 22.81 | 32.00 | ||||
Unknown | 23.68 | 24.05 | 5.44 | 7.06 | 25.87 | 23.52 | 6.73 | 6.00 | ||||
Multiple female without male | 5.18 | 6.75 | 11.66 | 9.67 | 4.85 | 3.70 | 10.23 | 14.00 | ||||
Multiple female + male | 11.22 | 11.69 | 15.09 | 11.15 | 11.41 | 9.07 | 8.77 | 6.00 | ||||
Embryos transferred | 2.23 ± 1.03 | 1.98 ± 0.79 | <.01 | 1.89 ± 0.46 | 1.94 ± 0.72 | .25 | 2.42 ± 0.84 | 2.43 ± 0.92 | .65 | 2.07 ± 0.30 | 2.28 ± 0.57 | <.01 |
First ET, % | 50.82 | 13.69 | 39.81 | 7.06 | 51.14 | 10.19 | 38.89 | 4.00 |
Note: NA = over 50% of data are missing.
Sites. Embryo cryopreservation and preeclampsia risk. Fertil Steril 2017.