TABLE 2.
Outcomes of singleton births from pregnancies achieved through ART with fresh versus cryopreserved-warmed ET, by egg source.
| Outcome | Autologous eggs | Donor eggs | ||||
|---|---|---|---|---|---|---|
| Fresh (n = 7,453) |
Cryopreserved (n = 1,052) |
P valuea (unadjusted) |
Fresh (n = 643) |
Cryopreserved (n = 269) |
P valuea (unadjusted) |
|
| Gestational age (wk), mean ± SD | 38.67 ± 2.13 | 38.61 ± 2.25 | .43 | 38.61 ± 2.33 | 37.95 ± 2.74 | .0002 |
| Infant sex (female), % | 48.20 | 48.29 | .98 | 48.21 | 51.67 | .35 |
| Preterm birth, <37 wk, % | 9.58 | 10.27 | .52 | 11.82 | 17.10 | .04 |
| Gestational diabetes, % | 7.30 | 7.89 | .49 | 9.33 | 8.55 | .71 |
| Gestational hypertension, % | 4.70 | 5.13 | .58 | 6.69 | 10.78 | .05 |
| Preeclampsia, any type, % | 4.29 | 7.51 | <.0001 | 12.13 | 10.78 | .56 |
| Preeclampsia without severe features | 2.55 | 3.99 | .007 | 7.31 | 5.58 | .34 |
| Preeclampsia with severe features | 1.41 | 2.95 | .0002 | 4.51 | 4.83 | .83 |
| Preeclampsia with preterm delivery | 1.48 | 2.76 | .002 | 3.89 | 4.83 | .64 |
| Chronic hypertension with superimposed preeclampsia | 0.43 | 0.95 | .03 | 0.62 | 0.74 | 1.00 |
| Eclampsia | 0.01 | 0.10 | .23 | 0.16 | 0.00 | 1.00 |
a
Categorical: χ2 test; continuous: t-test.
Sites. Embryo cryopreservation and preeclampsia risk. Fertil Steril 2017.