Table 2.

Prevalence of the individual features in 17 patients with Marfan syndrome diagnosed in Olmsted County from 1976 to 2005

Study parameter	Fulfilling Ghent (N = 17)
Skeletal system involved	10
Reduced upper to lower segment ratio (<0.85) or arm span to height ratio >1.05	8
Wrist and thumb signs	3
Scoliosis of >20° or spondylolisthesis	2
Medial displacement of the medial malleolus causing pes planus	2
Marfanoid habitus, not otherwise specified	1
Ocular system involved	11
Ectopia lentis	4
Othera	11
Cardiovascular system involved	15
Dilatation of ascending aorta	12
Dissection of ascending aorta	3
Mitral valve prolapse with or without mitral valve regurgitation	9
Dilatation of descending thoracic or abdominal aorta at <50 years	3
Dissection of descending thoracic or abdominal aorta at <50 years	1
Lungs involved	1
Spontaneous pneumothorax	1
Skin and integument involved	3
Recurrent or incisional hernia	1
Striae atrophica from puberty	3
Genetics	11
Having parent, child, or sibling who meets diagnostic criteria independently	11
Presence of a mutation in FBN1 known to cause Marfan syndrome	2

^aNon-criteria-fulfilling ocular involvement: myopia, hyperopia, astigmatism, strabismus, retinal detachment, amblyopia, and blurred vision.