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Ganglioside-liposomes bind Siglec-1 on THP-1 human monocyte/macrophage cells and are internalized. Fluorescently-labeled ganglioside-liposomes were incubated with THP1 cells overexpressing Siglec-1, and binding at 4 °C or uptake at 37 °C determined by flow cytometry. Binding or uptake of ganglioside-liposomes at different concentrations are shown. Data are from reference [48]
