Table 2.
Trends in Dialysis-Requiring AKI–Associated In-Hospital Mortality in People With Versus Without Diabetes, by Age and Sex, United States 2000-2015
| DM | AKI Hospitalization Rate, per 100 persons (95% CI) |
Trend 1a |
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|---|---|---|---|---|---|---|---|---|
| 2000 | 2005 | 2010 | 2015 | Year | Δ/y | P | ||
| Total b | ||||||||
|
| ||||||||
| Y | 23.1 (18.2-28.0) | 14.7 (11.7-17.7) | 12.0 (9.9-14.0) | 15.2 (12.0-18.4) | 2000-2015 | −3.9% | 0.01 | |
|
| ||||||||
| N | 34.4 (32.0-36.8) | 33.4 (31.6-35.2) | 28.7 (27.3-30.1) | 28.4 (26.6-30.2) | 2000-2015 | −2.0% | <0.001 | |
|
| ||||||||
| Sex b | ||||||||
|
| ||||||||
| Male | Y | 13.5 (11.0-16.0) | 9.4 (7.7-11.0) | 5.3 (4.5-6.1) | 5.9 (4.7-71) | 2000-2015 | −5.4% | <0.001 |
|
| ||||||||
| N | 20.0 (18.9-21.0) | 18.5 (17.7-19.3) | 14.7 (14.1-15.3) | 14.9 (14.1-15.6) | 2000-2015 | −1.6% | <0.001 | |
|
| ||||||||
| Female | Y | 9.6 (7.2-12.0) | 5.3 (3.9-6.6) | 6.7 (5.4-8.0) | 9.3 (7.2-11.3) | 2000-2015 | −2.1% | 0.2 |
|
| ||||||||
| N | 14.4 (13.1-15.8) | 15.0 (14.0-16.0) | 14.0 (13.2-14.8) | 13.5 (12.4-14.6) | 2000-2015 | −2.4% | 0.004 | |
|
| ||||||||
| Age Group | ||||||||
|
| ||||||||
| 18-44 y | Y | 8.9 (5.5-12.2) | 5.8 (3.7-7.8) | 4.1 (2.6-5.5) | 7.3 (4.9-9.8) | 2000-2015 | −3.2% | 0.2 |
|
| ||||||||
| N | 9.4 (8.2-10.6) | 12.8 (11.8-13.7) | 8.2 (7.4-9.0) | 9.7 (8.6-10.8) | 2000-2015 | −1.5% | 0.2 | |
|
| ||||||||
| 45-64 y | Y | 11.0 (9.8-12.2) | 6.5 (5.8-7.2) | 6.9 (6.4-7.4) | 7.3 (6.7-7.9) | 2000-2015 | −3.8% | <0.001 |
|
| ||||||||
| N | 23.3 (22.2-24.5) | 19.7 (18.9-20.4) | 21.3 (20.7-21.9) | 18.3 (17.7-19.0) | 2000-2015 | −1.8% | 0.002 | |
|
| ||||||||
| 65-74 y | Y | 20.4 (18.8-22.1) | 9.7 (8.6-10.7) | 10.7 (10.0-11.5) | 6.1 (5.5-6.8) | 2000-2015 | −6.2% | <0.001 |
|
| ||||||||
| N | 31.6 (30.1-33.2) | 22.6 (21.6-23.6) | 20.8 (20.0-21.5) | 22.0 (21.1-22.9) | 2000-2015 | −2.1% | <0.001 | |
|
| ||||||||
| ≥75 y | Y | 21.3 (19.4-23.2) | 18.1 (16.8-19.5) | 10.0 (9.3-10.7) | 12.0 (11.1-13.0) | 2000-2015 | −6.3% | <0.001 |
|
| ||||||||
| N | 29.6 (28.5-30.8) | 25.3 (24.5-26.1) | 21.9 (21.3-22.5) | 19.6 (18.8-20.3) | 2000-2015 | −3.6% | <0.001 | |
Abbreviations: Δ/y, annual change; AKI, acute kidney injury; CI, confidence interval; DM, diabetes mellitus; N, no; Y, yes.
Data sources: National Center for Health Statistics, National Health Interview Survey, and National Inpatient Sample.
a
Indicates the year in which linear trends change in either direction or magnitude.
b
Total and sex-specific rates are age-standardized.