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Integrated representation of the metabolic and molecular processes associated with the 9 metabolites composing the early predictive signature of cognitive decline. In green (metabolites showing decline-related increase: glucose, serine, triglycerides, and sphingomyelin) and in red (metabolites showing decline-related decrease: β-hydroxybutyrate, acetone, citrate, succinate, and methionine). Made with Biorender.com.
