FIG. 2.

Effect of LMB on the function of Rev and other Rev-like proteins in the CAT assay. (A) pDM128 (RRE-containing RNA) was transfected with pRSVRev or Δ3FIV or with neither in the absence or presence of LMB. LMB inhibits Rev- and Δ3FIV-mediated CAT activities of RRE-containing RNA by 50 and 80%, respectively. (B) pDM138ERRE-1-containing RNA either was or was not transfected with pRS-ERev in the presence and absence of LMB. LMB inhibits ERev-mediated CAT activity by 72%.