FIG. 4.

Effect of LMB on the function of the PRE and CTE in the CAT assay. pDM128 (RRE-containing RNA) either was or was not transfected with pRSVRev in the presence and absence of LMB; 138PRE (PRE-containing RNA) and 138CTE (CTE-containing RNA) were transfected in the presence and absence of LMB. LMB inhibits Rev export of RRE-containing RNA by 60%. LMB does not affect the cytoplasmic accumulation of PRE- or CTE-containing RNAs.