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. 2024 Mar 25;15:1353023. doi: 10.3389/fendo.2024.1353023

Table 1.

Characteristics of the included studies.

Author Year Sex (F/M) CPP group Non-CPP group Feature Classifier Optimal
classifier
SPE SEN AUC
N Age (mean ± SD), y N Age (mean ± SD), y
Pan et al. (16) 2020 F 1153 7.056 ± 1.13 1370 7.476 ± 1.09 General features,
Clinical features,
Laboratory features,
BA,US
XGBoost XGBoost 77.88 85.71 0.88
Huynh et al. (17) 2022 F 524 7.2 ± 1.8 90 7.5 ± 1.5 General features,
Clinical features,
Laboratory features,
BA
kNN, GNB, LR, RF, XGBoost RF 89.30 96.60 0.97
Pang et al. (18) 2022 F 408 10.9 5119 10.8 General features,
Clinical features,
Laboratory features
LR,DT,
Adaboost, SVM,
RF,kNN,GBM,GNB,et al
GBM 93.22 34.39 0.79
Pan et al. (19) 2019 F 791 7.52 ± 0.99 966 7.07± 1.11 General features,
Clinical features,
Laboratory features
XGBoost,RF,SVM,DT XGBoost 85.39 77.94 0.89
Chen et al. (20) 2023 F 137 8.51 24 8.55 General features,
Clinical features,
Laboratory features
LR, RF, GBM, XGBoost LR 85.7 95.2 0.88
Zou et al. (21) 2023 F 185 7.52± 0.56 307 7.21± 0.76 General features,
Clinical features,
Laboratory features
US, MRI Radiomics
RF, DT, SVM, GNB, LR LR 85.7 72.7 0.86

F, female; M, male; N, number of patients; CPP, central precocious puberty; BA, bone age; US, ultrasonography; MRI, magnetic resonance imaging; XGBoost, extreme gradient boosting; kNN, k- nearest neighbor algorithm; GNB, gaussian naive bayes; LR, logistic regression; RF, random forest; DT, decision tree; SVM, support vector machine; GBM, gradient boosting machine; SPE, Specificity; SEN, Sensitivity; AUC, area under the curve.