Table 1.
Population characteristics by atovaquone-proguanil exposure in pregnancy, 2003–2014.a
| Characteristics | Pregnancies |
Infants (singleton) |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Unexposed | Exposed | Unexposed | Exposed | ||||||
| Total | 197,835 | 50 | 160,892 | 36 | |||||
| Maternal age at conception | |||||||||
| Median (range) | 24.0 (17–54) | 30.5 (19–43) | 24.0 (17–54) | 30.0 (19–39) | |||||
| 17–19 years | 15,974 | (8.1) | 1 | (2.0) | 12,929 | (8.0) | 1 | (2.8) | |
| 20–24 years | 85,303 | (43.1) | 10 | (20.0) | 70,058 | (43.5) | 9 | (25.0) | |
| 25–29 years | 54,311 | (27.5) | 11 | (22.0) | 44,960 | (27.9) | 7 | (19.4) | |
| 30–34 years | 28,374 | (14.3) | 19 | (38.0) | 23,123 | (14.4) | 15 | (41.7) | |
| 35 + years | 13,873 | (7.0) | 9 | (18.0) | 9822 | (6.1) | 4 | (11.1) | |
| Maternal race/ethnicity | |||||||||
| Non-Hispanic white | 94,718 | (47.9) | 22 | (44.0) | 77,537 | (48.2) | 17 | (47.2) | |
| Non-Hispanic black | 54,052 | (27.3) | 7 | (14.0) | 43,280 | (26.9) | 3 | (8.3) | |
| Hispanic | 27,159 | (13.7) | 11 | (22.0) | 22,026 | (13.7) | 10 | (27.8) | |
| Other or unknown | 21,906 | (11.1) | 10 | (20.0) | 18,049 | (11.2) | 6 | (16.7) | |
| Maternal service branch | |||||||||
| Army | 68,413 | (34.6) | 17 | (34.0) | 53,871 | (33.5) | 12 | (33.3) | |
| Navy | 51,276 | (26.0) | 14 | (28.0) | 42,351 | (26.3) | 11 | (30.6) | |
| Air Force | 58,699 | (29.7) | 18 | (36.0) | 48,523 | (30.2) | 13 | (36.1) | |
| Marine Corps | 15,065 | (7.6) | 1 | (2.0) | 12,475 | (7.8) | 0 | (0.0) | |
| Coast Guard | 4382 | (2.2) | 0 | (0.0) | 3672 | (2.3) | 0 | (0.0) | |
| Maternal rank | |||||||||
| Enlisted | 170,940 | (86.4) | 26 | (52.0) | 138,803 | (86.3) | 20 | (55.6) | |
| Officer | 26,895 | (13.6) | 24 | (48.0) | 22,089 | (13.7) | 16 | (44.4) | |
| Maternal education | |||||||||
| No high school diploma | 11,229 | (5.7) | 0 | (0.0) | 8724 | (5.4) | 0 | (0.0) | |
| High school diploma | 137,048 | (69.3) | 16 | (32.0) | 111,613 | (69.4) | 13 | (36.1) | |
| More than high school | 46,026 | (23.3) | 32 | (64.0) | 37,737 | (23.5) | 22 | (61.1) | |
| Unknown | 3532 | (1.8) | 2 | (4.0) | 2818 | (1.8) | 1 | (2.8) | |
| Maternal marital status | |||||||||
| Married | 140,861 | (71.2) | 41 | (82.0) | 117,820 | (73.2) | 30 | (83.3) | |
| Unmarried or unknown | 56,974 | (28.8) | 9 | (18.0) | 43,072 | (26.8) | 6 | (16.7) | |
| Timing of antimalarial exposure | |||||||||
| First trimester | N/A | 47 | (94.0) | N/A | 33 | (91.7) | |||
| Second or third trimester | N/A | 3 | (6.0) | N/A | 3 | (8.3) | |||
| Receipt of vaccination(s) generally contraindicated in pregnancy | |||||||||
| No | 180,945 | (91.5) | 40 | (80.0) | 146,383 | (91.0) | 27 | (75.0) | |
| Yes | 16,890 | (8.5) | 10 | (20.0) | 14,509 | (9.0) | 9 | (25.0) | |
a
Data presented as N (percent %).