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. 2023 Nov 27;28(1):2279813. doi: 10.1080/13510002.2023.2279813

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 4. — Hypoxia induces fibroblast activation in vitro. (A–C) WI38 fibroblast cells were treated with conditioned A549 culture medium under normoxia (NX) and hypoxia (HX) conditions for 24 h, then were harvested for analyzing the protein levels of FAP (A and B) and α-SMA (A and C) by Western blot. (D-F) The protein level of FAP (D and E) and α-SMA (D and F) in WI38 cells under normoxia (NX) and hypoxia (HX) conditions for 24 h. G, Wound closure rate of WI38 cells in wound healing assay under normoxia (NX) and hypoxia (HX) condition for the first 24 h. n = 3 wells.