Table 1.
Characteristics of liver cancer cases and controls, Southern Community Cohort Study
| Characteristic | Liver cancer status | p value | |
|---|---|---|---|
| cases (N = 50) | controls (N = 151) | ||
| Age, years, mean (std) | 53.0 (6.0) | 53.4 (8.4) | 0.77 |
| Age <65 years, n (%) | 47 (94) | 133 (88) | 0.24 |
| Age ≥65 years, n (%) | 3 (6) | 18 (12) | |
| Sex, n (%) | 0.002 | ||
| Female | 13 (26) | 77 (51) | |
| Male | 37 (74) | 74 (49) | |
| Race, n (%) | 0.62 | ||
| Black | 39 (78) | 107 (71) | |
| White | 10 (20) | 40 (26) | |
| All others | 1 (2) | 4 (3) | |
| Income, n (%) | 0.14 | ||
| <15 K | 38 (76) | 91 (61) | |
| 15 K–49 K | 10 (20) | 51 (34) | |
| 50 K+ | 2 (4) | 8 (5) | |
| Education, n (%) | 0.09 | ||
| <HS | 21 (42) | 46 (30) | |
| HS or equivalent/some college | 27 (54) | 84 (56) | |
| College+ | 2 (4) | 21 (14) | |
| Smoking status, n (%) | 0.001 | ||
| Current | 36 (72) | 68 (45) | |
| Former | 9 (18) | 30 (20) | |
| Never | 5 (10) | 53 (35) | |
| NSAID use, n (%) | 0.01 | ||
| Yes | 24 (48) | 43 (28) | |
| No | 26 (52) | 108 (72) | |
| BMI, n (%) | 28.4 (6.3) | 29.0 (6.2) | 0.55 |
| <25 | 19 (38) | 40 (27) | 0.50 |
| 25–29 | 14 (28) | 52 (35) | |
| 30–34 | 9 (18) | 32 (21) | |
| 35+ | 8 (16) | 25 (17) | |
| Alcohol consumption status, n (%) | 0.02 | ||
| None | 10 (20) | 61 (40) | |
| Moderate | 23 (46) | 58 (38) | |
| Heavy | 17 (34) | 32 (21) | |
| Cr, mg/mL, mean (std) | 1.2 (0.6) | 1.2 (0.7) | 0.79 |
| PGE-M, ng/mg Cr, mean (std) | 20.2 (18.2) | 14.7 (14.9) | 0.04 |
| PGD-M, ng/mg Cr, mean (std) | 3.5 (6.3) | 3.9 (5.2) | 0.68 |
| PGI-M, ng/mg Cr, mean (std) | 0.49 (0.84) | 0.22 (0.21) | 0.03 |
| 11dTxB2, ng/mg Cr, mean (std) | 1.24 (1.94) | 0.40 (0.63) | 0.004 |
| TN-E, ng/mg Cr, mean (std) | 7.9 (8.5) | 5.3 (7.2) | 0.03 |
p value was derived from t test for continuous variables and χ2 test for categorical variables.