Table 4.
Sample size calculation and assumption of postoperative complications for each surgical procedure
| Surgical procedure | All procedures | Pouch surgery | APR | TC |
|---|---|---|---|---|
| Patients with CDC complications, n (%) | 321/588 (54.59) | 214/425 (50.35) | 48/72 (66.67) | 59/91 (64.84) |
| XX % reduction in complications | 40 | 40 | 40 | 40 |
| Mean CCI±SD | 15.23±18.35 | 13.16±14.53 | 14.63±18.54 | 25.38±28.37 |
| Δ | 10 | 10 | 10 | 10 |
| Sample size/group (CDC) | 80 | 92 | 54 | 58 |
| Sample size/group (CCI) | 54 | 35 | 55 | 128 |
CDC, Clavien-Dindo classification; CCI, comprehensive Complication index; APR, abdominal perineal resection; TC, total colectomy.
CDC: calculated sample size to achieve 80% power by the χ2 test.
CCI: calculated sample size to achieve 80% power by the t test.