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Summary of sites within nt 127 to 390 of the CSFV IRES that are modified by DMS and CMCT (A) or cleaved by RNase V1 and RNase ONE (B). These chemical and enzymatic probes are indicated by symbols at the upper right of each panel. The results are displayed on a structure that is based on previous proposals (5, 34) and that takes into account the results presented here. The nomenclature used to describe CSFV domains and hairpins is adapted from proposals (11) for the HCV IRES.
