Table 2.

Bronchiolitis course and outcome in the four different study periodsData are presented as median [IQR] or absolute frequency (percentage). ANOVA or Kruskal-Wallis test for continuous variables, and Fisher exact test or Chi-squared test for categorical variables were used for comparison

	2018–2019	2020–2021	2021–2022	2022–2023	p
N	1618	121	1577	2014
Oxygen supplementation	959 (59)	69 (57)	1157 (73)	1527 (76)	< 0.001
Length of oxygen supplementation, days	0 [0–4]	1 [0–3]	2 [0–5]	2 [0–5]	< 0.001
Non-invasive ventilation support	470 (29)	42 (35)	726 (46)	1055 (52)	< 0.001
Invasive ventilation support	20 (1.2)	1 (0.8)	18 (1.1)	39 (1.9)	0.159
Intensive care unit admission	178 (11)	13 (11)	239 (15)	320 (16)	< 0.001
Length of intensive care stay, days	5 [3-7]	3 [2-6]	5 [3-7]	5 [4-8]	< 0.001
Length of intensive care stay ≥ 3, days	143 (80)	8 (62)	192 (80)	285 (89)	0.001
Extracorporeal membrane oxygenation	3 (0.2)	0 (0.0)	1 (0.1)	2 (0.1)	0.735
Length of the whole hospitalization, days	6 [4-8]	5 [4-6]	6 [4-8]	6 [4-8]	< 0.001
Length of the whole hospitalization ≥ 4 days	1352 (84)	91 (75)	1343 (85)	1758 (87)	< 0.001

Data are presented as median [IQR] or absolute frequency (percentage). ANOVA or Kruskal-Wallis test for continuous variables, and Fisher exact test or Chi-squared test for categorical variables were used for comparison