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. 2024 Apr 8;14:8250. doi: 10.1038/s41598-024-58684-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Illustration of tumor volume measured under different delivery schemes according to Fig. 2b. The vertical line on day 14 represents the first radiation pulse. (a) Group 1 (isotype control) and group 2 (PD-L1 antibody, every other day), both without radiation applied. (b) Group 6 (a single pulse of 40 Gy) and group 8 (two pulses of 20 Gy separated by 10 days), both with PD-L1 antibody administered every other day. (c) Group 3 (control) and group 4 (PD-L1 antibody, every other day), both with a single pulse of 20 Gy delivered on day 14. (d). Group 7 (control) and group 8 (PD-L1, every other day), both with two pulses delivered with an interval of 10 days.