Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Apr 8;14:8176. doi: 10.1038/s41598-024-58375-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Autophagy is hyperactivated in the quadriceps femoris muscle of KOA rats. (A) Changes in LC3 and P62 expression were assessed by Western blotting. Equal protein loading was normalized by GAPDH. Original blots/gels were presented in Supplementary Figs. S4–S6. *P < 0.05, **P < 0.01, ***P < 0.001. All data are expressed as mean ± SD, n = 3 for each group. (B) Abnormal morphology of autophagosomes and mitochondria in the quadriceps femoris muscle of KOA rats. Autophagosomes (red arrows). Images were acquired at 2500 × , scale bars = 5 μm. Images were acquired at 7000 × , scale bars = 2 μm. Control represents the blank control rats. Sham represents sham-operated group rats. KOA represents the KOA model group rats. KOA + CUR represents the treated group rats with feeding CUR.