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INS-DRiP is expressed in insulinoma tissue. Immunohistochemistry of Whipple procedure-derived human insulinoma sections with insulin (red), INS-DRiP (white), glucagon (green), and Hoechst (blue). (A) Islet–insulinoma interface (top panel) and insulinoma only (bottom panel) are shown for insulinoma 1. (B) Insulinoma 2 is shown. INS-DRiP colocalized with insulin+ cells (red arrow), glucagon+ cells (green arrow), and triple positive cells (white arrow). Scale bars=20 µm.
