Table 1.
Clinical characteristics of cases and controls included in association analyses after data quality control
Cases | Controls | |
Total | 573 | 1595 |
Females, n (%) | 290 (51) | 1169 (73) |
Age at diagnosis, mean (SD) | 54 (18) | – |
Age at sampling, mean (SD) | 59 (17) | 58 (14) |
GPA, n (%) | 434 (76) | – |
MPA, n (%) | 139 (24) | – |
PR3-ANCA+, n (%) | 411 (72) | – |
MPO-ANCA+, n (%) | 162 (28) | – |
ENT involvement,* n (%) | 380 (66) | – |
Kidney involvement,* n (%) | 383 (67) | – |
Pulmonary involvement,* n (%) | 303 (53) | – |
Relapse†, n (%) | 217 (54) | – |
*Defined as glomerulonephritis (kidneys) or any kind of pulmonary/ENT involvement, respectively.
†Missing data, n=172.
ANCA, antineutrophil cytoplasmic autoantibody; ENT, ear–nose–throat; GPA, granulomatosis with polyangiitis; MPA, microscopic polyangiitis; MPO, myeloperoxidase; PR3, proteinase 3.