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Inhibitor resistance of 487-derived virusesa
| Virus clone | IC50 (SD) (nM) | IC90 (SD) (nM) |
|---|---|---|
| 487WW | 2.4 (1.5) | 9 (6.6) |
| 487WM | 1,502 (487) | >3,125 |
| 487MM | 1,933 (322) | >3,125 |
| 487MW | 6.7 (2.4) | 23 (12) |
| 487Wm | 99 (59) | 448 (144) |
| 487Mm | 302 (195) | 1,041 (359) |
SQV IC50s and IC90s were measured in a single-cycle resistance assay on P4 cells.
