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. 2024 Mar 26;10(7):e27961. doi: 10.1016/j.heliyon.2024.e27961

Table 2.

Risk baseline factors for mortality analyzed by Cox regression model.

Variable Mortality (95%CI)) HR (95% CI) P aHR (95% CI) P
Age at diagnosis (years old)
 ∼5 0.045(0.110, 0.608) 1.0 1.0
 ∼12 0.081(0.600, 1.831) 3.070 (1.301, 7.245) 0.010 3.140 (1.331, 7.411) 0.009
 ∼18 0.944(-0.373, 6.037) 5.528 (1.454, 21.012) 0.012 5.451 (1.434, 20.724) 0.013
Age at ART initiation (years old)
 ∼5 0.072(0.087, 0.782) 1.0
 ∼12 0.051(0.304, 1.027) 1.338 (0.508, 3.522) 0.555
 ∼18 0.367(0.666, 4.476) 4.139 (1.377, 12.441) 0.011
ART site
 CDC based 0.072(0.322, 1.253) 1.0
 Hospital based 0.045(0.335, 1.022) 0.691 (0.317, 1.508) 0.354
Baseline Disclosure
 Yes 0.185(0.831, 3.231) 3.502 (1.605, 7.642) 0.002
 No 0.033(0.217, 0.696) 1.0
WHO clinical stages
 I 0.077(0.048, 0.727) 1.0
 II 0.179(0.014, 1.416) 1.911 (0.513, 7.118) 0.334
 III 0.073(0.276, 1.177) 2.193 (0.749, 6.419) 0.152
 IV 0.262(0.475, 3.19) 5.490 (1.742, 17.304) 0.003
ART regimens
 AZT+3TC + LPV/r 0.070(0.265, 1.131) 1.0
 D4T+3TC + LPV/r 1.017(-0.785, 4.851) 3.532 (0.774, 16.127) 0.103
 AZT+3TC + EFV/NVP 0.076(0.188, 1.035) 1.034 (0.408, 2.624) 0.943
 D4T+3TC + EFV/NVP 0.458(-0.44, 1.356) 0.857 (0.109, 6.701) 0.883
 ABC+3TC + LPV/r 0.182(0.112, 1.708) 1.139 (0.389, 3.335) 0.813
Baseline CD4+T cell count
 Low 0.121(-0.116, 0.358) 10.964 (1.459, 82.390) 0.020 8.309 (1.093, 63.135) 0.041
 Medium 0.075(0.185, 1.018) 4.977 (0.622, 39.800) 0.130 4.146 (0.416, 33.318) 0.181
 High 0.074(0.659, 1.854) 1.0 1.0
Baseline CD4+T cell percentage (%)
 <15 0.090(0.404, 1.57) 1.0
 ≥15 0.040(0.297, 0.906) 0.574 (0.264, 1.250) 0.162
Baseline VL (copies/ml)
 <1000 0.433(-0.171, 2.768) 1.0
 <100000 0.105(0.126, 1.132) 0.499 (0. 124, 1.997) 0.326
 ≥100000 0.041(0.368, 1.035) 2.941 (0.171, 1.994) 0.391
Period from diagnosis to ART (days)
 ≤14 0.226(0.140, 2.121) 1.0
 >14 0.033(0.376, 0.963) 0.567 (0.212, 1.512) 0.257