Table 2.
Variable | Mortality (95%CI)) | HR (95% CI) | P | aHR (95% CI) | P |
---|---|---|---|---|---|
Age at diagnosis (years old) | |||||
∼5 | 0.045(0.110, 0.608) | 1.0 | 1.0 | ||
∼12 | 0.081(0.600, 1.831) | 3.070 (1.301, 7.245) | 0.010 | 3.140 (1.331, 7.411) | 0.009 |
∼18 | 0.944(-0.373, 6.037) | 5.528 (1.454, 21.012) | 0.012 | 5.451 (1.434, 20.724) | 0.013 |
Age at ART initiation (years old) | |||||
∼5 | 0.072(0.087, 0.782) | 1.0 | |||
∼12 | 0.051(0.304, 1.027) | 1.338 (0.508, 3.522) | 0.555 | ||
∼18 | 0.367(0.666, 4.476) | 4.139 (1.377, 12.441) | 0.011 | ||
ART site | |||||
CDC based | 0.072(0.322, 1.253) | 1.0 | |||
Hospital based | 0.045(0.335, 1.022) | 0.691 (0.317, 1.508) | 0.354 | ||
Baseline Disclosure | |||||
Yes | 0.185(0.831, 3.231) | 3.502 (1.605, 7.642) | 0.002 | ||
No | 0.033(0.217, 0.696) | 1.0 | |||
WHO clinical stages | |||||
I | 0.077(0.048, 0.727) | 1.0 | |||
II | 0.179(0.014, 1.416) | 1.911 (0.513, 7.118) | 0.334 | ||
III | 0.073(0.276, 1.177) | 2.193 (0.749, 6.419) | 0.152 | ||
IV | 0.262(0.475, 3.19) | 5.490 (1.742, 17.304) | 0.003 | ||
ART regimens | |||||
AZT+3TC + LPV/r | 0.070(0.265, 1.131) | 1.0 | |||
D4T+3TC + LPV/r | 1.017(-0.785, 4.851) | 3.532 (0.774, 16.127) | 0.103 | ||
AZT+3TC + EFV/NVP | 0.076(0.188, 1.035) | 1.034 (0.408, 2.624) | 0.943 | ||
D4T+3TC + EFV/NVP | 0.458(-0.44, 1.356) | 0.857 (0.109, 6.701) | 0.883 | ||
ABC+3TC + LPV/r | 0.182(0.112, 1.708) | 1.139 (0.389, 3.335) | 0.813 | ||
Baseline CD4+T cell count | |||||
Low | 0.121(-0.116, 0.358) | 10.964 (1.459, 82.390) | 0.020 | 8.309 (1.093, 63.135) | 0.041 |
Medium | 0.075(0.185, 1.018) | 4.977 (0.622, 39.800) | 0.130 | 4.146 (0.416, 33.318) | 0.181 |
High | 0.074(0.659, 1.854) | 1.0 | 1.0 | ||
Baseline CD4+T cell percentage (%) | |||||
<15 | 0.090(0.404, 1.57) | 1.0 | |||
≥15 | 0.040(0.297, 0.906) | 0.574 (0.264, 1.250) | 0.162 | ||
Baseline VL (copies/ml) | |||||
<1000 | 0.433(-0.171, 2.768) | 1.0 | |||
<100000 | 0.105(0.126, 1.132) | 0.499 (0. 124, 1.997) | 0.326 | ||
≥100000 | 0.041(0.368, 1.035) | 2.941 (0.171, 1.994) | 0.391 | ||
Period from diagnosis to ART (days) | |||||
≤14 | 0.226(0.140, 2.121) | 1.0 | |||
>14 | 0.033(0.376, 0.963) | 0.567 (0.212, 1.512) | 0.257 |