Table 3.
Univariable and multivariable analysis in patients with gynecological malignant tumor for OS
| Clinicopathologic factors | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | value | HR | 95% CI | value | |
| Age | 3.964 | 1.885–8.336 | 0.001 | 2.847 | 1.108–7.32 | 0.05 |
| Menopause | 4.362 | 1.518–12.536 | 0.01 | 2.729 | 0.737–10.109 | 0.133 |
| BMI index | 0.563 | 0.445–1.555 | 0.563 | |||
| Albumin | 0.113 | 0.048–0.267 | 0.001 | 0.824 | 0.291–2.33 | 0.715 |
| WBC | 1.528 | 0.411–5.681 | 0.527 | |||
| Hb | 0.331 | 0.159–0.687 | 0.01 | 0.648 | 0.278–1.51 | 0.315 |
| MCV | 1.701 | 0.470–6.156 | 0.418 | |||
| CRP | 11.918 | 4.842–29.334 | 0.001 | 7.644 | 2.215–26.374 | 0.001 |
| ALT | 1.166 | 0.157–8.654 | 0.881 | |||
| CA125 | 9.055 | 3.144–26.075 | 0.001 | 5.445 | 1.365–21.727 | 0.05 |
| CEA | 3.917 | 1.780–8.620 | 0.001 | 4.492 | 1.759–11.471 | 0.05 |
| AFP | 2.814 | 0.655–12.086 | 0.164 | |||
| CA153 | 4.601 | 2.212–9.572 | 0.001 | 1.564 | 0.637–3.84 | 0.329 |
| Ferritin | 2.72 | 1.324–5.590 | 0.01 | 0.792 | 0.351–1.787 | 0.574 |
| Lymphatic metastasis | 4.795 | 2.261–10.166 | 0.001 | 1.022 | 0.359–2.909 | 0.968 |
| Ascites | 6.915 | 3.192–14.979 | 0.001 | 1.048 | 0.359–3.056 | 0.932 |
| Tumor size | 2.201 | 1.016–4.766 | 0.05 | 0.395 | 0.154–1.012 | 0.053 |
| FIGO stage | 2.989 | 2.058–4.342 | 0.001 | 1.235 | 0.301–5.074 | 0.77 |
OS: overall survival; HR, hazard ratio; CI: confidence interval; BMI, body mass index; ALB, albumin; WBC, white blood cell; Hb, hemoglobin; MCV, mean corpuscular volume; CRP, C-reactive protein; ALT, alanine aminotransferase; CA125, cancer antigen 125; CEA, carcinoembryonic antigen; AFP, alpha fetoprotein; CA153, cancer antigen 153; FIGO, Inter-national Federation of Gynecology and Obstetrics.