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. 2024 Feb 26;15:1337185. doi: 10.3389/fmicb.2024.1337185

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Copyright © 2024 Liu, Liu, Zhang and Fan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic patterns in the experiment groups. (A) PCA analysis between healthy control group and ethanol-induced group. (B) Clustering analysis of OPLS-DA in the healthy control group and ethanol-induced group. (C) PCA analysis between B. coagulans-treated group and ethanol-induced group. (D) Clustering analysis of OPLS-DA in the B. coagulans-treated group and ethanol-induced group. (E) PCA analysis between B. coagulans-treated group and healthy control group. (F) Clustering analysis of OPLS-DA in the B. coagulans-treated group and healthy control group. (G) The KEGG pathways in the healthy control group and ethanol-induced group. (H) The KEGG pathways in the B. coagulans-treated group and ethanol-induced group. (I) The KEGG pathways in the B. coagulans-treated group and healthy control group. (J) Pathway analysis for group ethanol-induced vs. healthy control. (K) Pathway analysis for group B. coagulans-treated vs. ethanol-induced. (L) Pathway analysis for group B. coagulans-treated vs. healthy control. Ctrl, healthy control group; EtOH, ethanol-induced group; B. co, supplementation of B. coagulans group.