Table 3. A comparison of various studies on frequency of PDL1 in breast cancers from different parts of India .
Study | Present Study | Bhardwaj et al. [24] | Ghosh et al. [23] | Sharma et al. [22] | Mehan et al. [21] | Punhani et al [26]. |
1. Region of India | South India | South India | East India | North India | North India | North India |
2. Year of publication | - | 2019 | 2021 | 2021 | 2022 | 2023 |
3. Number of patients | 120 | 132 | 107 | 40 | 103 | 150 |
a. Metastatic disease | 120 | NA | Nil | 20 | 14 | NA |
b. Non-metastatic disease | - | NA | 107 | - | 89 | NA |
4. Molecular classification | TNBC | All including TNBC | TNBC | TNBC | All subtypes | All subtypes |
5. Median age | 46 | NA | Ventana SP 142 | 40 to 60 | 51 | NA |
6. Platform used | 22C3 | RTqPCR | - | - | SP 263 | NA |
7. PDL1 Positivity | 31.66% in tumor and immune cells | 52% in immune cells 13% in tumor cells amongst TNBC | NA | 32.5% in tumor cells | 59.2% in Immune cells 37.9% in tumor cells | 14.67 |