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DinJ inhibits inflammasome activation to evade clearance of host immune system. (A–C) ELISA analysis of IL-1β (A), IL-18 (B), and IL-6 (C) in the serum of WT mouse infected with ΔfliC or ΔfliCΔdinJ. (D and E) Assessment of bacterial loading in the liver (D) and spleen (E) of WT mouse infected with ΔfliC or ΔfliCΔdinJ. Statistical significance was determined at P values of <0.01 (**) or <0.001 (***) using the Student’s t-test.
