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. 2024 Mar 25;15:1364658. doi: 10.3389/fneur.2024.1364658

Figure 2.

Figure 2

Robustness assessment of Aβ42/40 ratio for predicting amyloid PET imaging results. (A) Densities of plasma Aβ42/40 ratio by LC-MS/MS in ADRC cohort with and without 10% bias (22% total, upper plot) and 2% measured bias (lower plot) added. (B) Scatterplots of Aβ42 and Aβ40 to illustrate proximity to cutoffs defining indeterminate risk and scatterplots of Aβ42/40 ratio with and without 10% CV added noise (upper plot) and 6% added CV (measured) noise (lower plot). Aβ, beta-amyloid; ADRC, Alzheimer’s Disease Research Center; CI, confidence interval; PET, positron emission tomography.