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. 2021 Mar 20;2(1):19–31. doi: 10.17816/CP66

Table 3. Table 3. Immunological parameters and systemic inflammation markers among patients with episodic schizophrenia (n=20), continuous schizophrenia (n=16) and among the controls (n=30).

The results are presented as Median (25 quartile; 75 quartile). * - differences with controls, p<0.05. ** - differences between groups, p<0.05.

Parameters Episodic schizophrenia Continuous schizophrenia Controls
Humoral component parameters IgA, [g/l] 2.97 (2.31; 3.35) 3.09 (2.17; 3.23) 2.79 (2.58; 3.09)
IgM, [g/l] 1.43 (0.93; 2.09) 1.05 (0.73; 1.46) 0.9435 (0.71; 1.3)
IgG, [g/l] 13.69 (9.73; 15.19) 13.62 (11.07; 15.81) 12.74 (10.15; 14.44)
CIC, [units] 73 (58; 104)** 103 (84; 192)*,** 76 (54; 95.5)
Acute phase proteins, signalling proteins (cytokines) CRP, [mg/l] 5.48 (0.81; 20.33)* 3.3 (1.93; 8.4)* 1.08 (0.38; 2.53)
IL-4, [pg/ml] 2.33 (1.72; 4.61) 3.5 (1.06; 5.13) 4.19 (1.39; 8.31)
IL-10, [pg/ml] 5.03 (2.62; 6.76) 5.91(3.03; 8.28) 4.28 (1.39; 8.31)
IFNγ, [pg/ml] 44.69 (26.88; 138.78) 44.69 (19.38; 83.33) 28.5335 (20.31; 44.32)
IL-8, [pg/ml] 34.54 (11.19; 214.76)* 40.16 (12.61; 94.15)* 11.81 (7.31; 23.59)
TNFα, [pg/ml] 2.09 (1.75; 3.08) 1.62 (1.30; 2.23) 1.69 (1.40; 2.84)
IL-6, [pg/ml] 6.27 (4.02; 67.20) 5.39 (2.55; 10.85) 4.262 (2.42; 8.27)
Cell-mediated component parameters CD45+CD3+, [%] 77.60 (74.60; 79.50)** 71.05 (68.40; 74.20)** 75.95 (71.85;78.20)
CD45+CD3+CD4+, [%] 44.00 (39.20; 47.70) 39.95 (38.10; 44.00) 43.65 (36.60; 48.40)
CD45+CD3+CD8+, [%] 25.8 21.40; 31.20) 23.85 (22.00; 28.80) 26.3 (23.8; 27.00)
CD45+CD3+CD4+CD25+CD127-, [%] 3.3(2.65; 3.45) 1.85 (1.40; 3.05) 2.45 (2.15; 3.30)
CD45+CD3+CD4+CD25+CD127- % from CD45+CD3+CD4+ lymphocytes, [%] 6.85 (6.05; 7.50)* 4.90 (3.6; 6.9) 4.75 (4.60; 5.55)
CD45+CD3-CD16/56+, [%] 10.60 (7.10; 13.40) 11.90 (9.60; 16.50) 11.90 (8.30; 16.50)
CD45+CD3+CD16/56+, [%] 3.40 (2.40; 6.40) 3.90 (2.60; 8.00) 4.9 (1.30; 7.50)
CD45+CD3-CD19+, [%] 10.40 (8.00; 13.00)** 14.00 (11.00; 18.30)*,** 11.40 (9.70; 12.20)