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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Am Heart J. 2023 Jun 12;264:153–162. doi: 10.1016/j.ahj.2023.06.005

Table 4.

Association between Serum Biomarker Concentrations and Cardiac Dimensions as Measured by Cardiac Magnetic Resonance Imaging, Adjusted for Age at Diagnosis, Time Since Diagnosis, Race, and Ethnicity*

Log of %LGE Log of LV Mass
(BSA-adjusted)
Log of LV
Mass/
LVEDV
Log of LV
Mass /
LVESV
Log
Interventricular
Septal
Thickness
Serum
Biomarker
N β
(SE)
P-
value
N β
(SE)
P-
value
N β
(S
E)
P-
value
N β
(S
E)
P-
value
N β
(S
E)
P-
value
NT-proBN p, pg/mL 44 0.09(0.09) 0.31 4 8 0.20(0.03) <0.001 47 0.21(0.03) <0.001 47(0.04) 0.16 0.001 5 9 0.19(0.02) <0.001
Cardiac troponi n-T, ng/mL 44 0.03(0.20) 0.90 48 0.18(0.09) 0.05 47 0.12(0.09) 0.21 47 0.13(0.11) 0.22 59 0.03(0.08) 0.69

Abbreviations: LGE, late gadolinium enhancement; LV, left ventricle; BSA, body surface area; NT-proBNP, N-terminalpro B-type natriuretic peptide.

*

Four patients with 0% LGE of LV mass were excluded because zero cannot be log-transformed.

Four patients with LAMP2 mutations were excluded from the association analysis.