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. 2024 Apr 9;14:8315. doi: 10.1038/s41598-024-58985-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differences in specific genera observed between diagnostic groups, Volcano plot showing results from the differential abundance analysis (a), and boxplots of selected genera (b). Differential abundance tests were performed with cell counts as normalization factors in DESeq2 performing both likelihood ratio test, comparing all diagnostic groups, and a Wald test to make pairwise comparisons between diagnostic groups. p-values in the Wald test were Benjamini–Hochberg corrected.