. 2024 Mar 27;6(2):fcae105. doi: 10.1093/braincomms/fcae105

Table 3.

Morphometric MRI data

		Multivariate				Univariate^b
		F (P)^*		DYT-SGCE (n = 19)	HV (n = 24)	F (P)^**
Mismatch detection functional module
Pre-SMA	Merged	1.53 (0.69)	VBM^a	0.33 ± 0.01	0.31 ± 0.01	-
			MD^a	0.0006 ± 0.00002	0.0007 ± 0.00001	-
SMA proper	Merged	2.49 (0.29)	VBM^a	0.27 ± 0.01	0.25 ± 0.01	-
			MD^a	0.0006 ± 0.00001	0.0006 ± 0.00001	-
IPL	Left	2.30 (0.31)	VBM^a	0.30 ± 0.02	0.28 ± 0.01	-
			MD^a	0.0003 ± 0.000003	0.0003 ± 0.000002	-
	Right	0.85 (1.00)	VBM^a	0.36 ± 0.02	0.34 ± 0.01	-
			MD^a	0.0004 ± 0.000004	0.0004 ± 0.000003	-
Match detection functional module
Insula	Left	0.18 (1.00)	VBM^a	0.38 ± 0.01	0.38 ± 0.01	-
			MD^a	0.0006 ± 0.00001	0.0006 ± 0.000004	-
	Right	1.75 (0.38)	VBM^a	0.42 ± 0.01	0.40 ± 0.01	-
			MD^a	0.0007 ± 0. 00001	0.0007 ± 0.000005	-
Precuneus	Left	1.30 (0.57)	VBM^a	0.31 ± 0.01	0.29 ± 0.01	-
			MD^a	0.0006 ± 0.00001	0.0006 ± 0.00001	-
	Right	1.94 (0.32)	VBM^a	0.31 ± 0.01	0.29 ± 0.01	-
			MD^a	0.0006 ± 0.00001	0.0006 ± 0.00001	-
Action-outcome prediction functional module
Putamen	Left	0.53 (1.00)	VBM^a	0.30 ± 0.01	0.29 ± 0.01	-
			MD^a	0.0005 ± 0.00001	0.0005 ± 0.000005	-
	Right	1.44 (0.50)	VBM^a	0.30 ± 0.01	0.29 ± 0.01	-
			MD^a	0.0005 ± 0.00001	0.0005 ± 0.000004	-
Cerebellum	Left	5.23 (0.02)	VBM^a	0.49 ± 0.01	0.47 ± 0.01	10.76 (0.004)
			MD^a	0.0006 ± 0.000005	0.0006 ± 0.000004	6.84 (0.03)
	Right	4.33 (0.04)	VBM^a	0.51 ± 0.01	0.49 ± 0.01	8.67 (0.01)
			MD^a	0.0006 ± 0.00001	0.0006 ± 0.000004	4.23 (0.09)

^aReported as mean ± Standard Error of the Mean.

^bTest provided only if difference in multivariate analysis.

*ANCOVA analysis (P corrected with Bonferroni correction for multiple comparisons) with age, sex, total intracranial volume, quality parameters (weighted overall image quality and absolute motion) as co-variables of non-interest.

**ANCOVA analysis (P corrected with Bonferroni correction for multiple comparisons) with age, sex, total intracranial volume and quality parameters (weighted overall image quality for voxel-based morphometry or absolute motion for MD) as co-variables of non-interest.

Significant test results in bold.

DYT-SGCE, myoclonus dystonia; HV, healthy volunteers; pre-SMA, pre-supplementary motor area; SMA, supplementary motor area; IPL, inferior parietal lobule; ROI, region of interest; VBM, voxel-based morphometry; MD, mean diffusivity.