Table VI.
Comparison of operative and postoperative outcomes after propensity score matching.
| Outcomes | Post-match all (n=70) | STH (n=35) | ANH (n=35) | P-value |
|---|---|---|---|---|
| Operative results | ||||
| Procedure | 0.568b | |||
| Pancreaticoduodenectomy | 50 (71.4) | 26 (74.3) | 24 (68.6) | |
| Distal pancreatectomy | 19 (27.1) | 9 (25.7) | 10 (28.6) | |
| Total pancreatectomy | 1 (1.4) | 0 (0.0) | 1 (2.9) | |
| Portal vein resection | 9 (12.9) | 4 (11.4) | 5 (14.3) | >0.999b |
| Operation time, min | 310 (129–619) | 261 (139–619) | 327 (129–587) | 0.042 |
| Anesthesia time, min | 374 (187–680) | 368 (226–676) | 392 (187–680) | 0.086 |
| Intraoperative blood loss, ml | 728 (130–2,200) | 570 (130–2,000) | 970 (150–2,200) | <0.001 |
| IBL >20% in CBV | 33 (47.1) | 10 (28.6) | 23 (65.7) | 0.002 |
| Blood volume removed, ml | 0 (0–800) | 0 (0–0) | 800 (400–800) | <0.001 |
| Intraoperative fluid given, ml | 3,700 (1,300–7,500) | 3,200 (1,300-7.500) | 4,000 (2,550–6,300) | <0.001 |
| Intraoperative albumin, ml | 0 (0–750) | 0 (0–500) | 0 (0–750) | 0.138 |
| Intraoperative FFP, ml | 0 (0–0) | 0 (0–0) | 0 (0–0) | - |
| Intraoperative PC, ml | 0 (0–0) | 0 (0–0) | 0 (0–0) | - |
| Total fluid volume administered, ml | 4,075 (1,300–8,000) | 3,200 (1,300–8,000) | 4,850 (2,950–7,600) | <0.001 |
| Intraoperative urine output, ml | 500 (20–1,550) | 430 (188–1,550) | 530 (20–1,550) | 0.332 |
| Total in-out balance, ml | 2,368 (485–5,500) | 1,935 (485–5,500) | 2,670 (1,190–4,555) | 0.003 |
| Total in-out balance, ml/kg/ha | 6.5 (1.8–13.9) | 6.3 (1.8–11.2) | 6.6 (3.2–13.9) | 0.104 |
| Postoperative results | ||||
| Postoperative complications (Clavien- | 13 (18.6) | 4 (11.4) | 9 (25.7) | 0.124b |
| Dindo classification grade ≥3) | ||||
| Pancreatic fistula (ISGPF grade ≥B) | 11 (15.7) | 4 (11.4) | 7 (20.0) | 0.324b |
| Delayed gastric emptying (ISGPS grade ≥B) | 9 (12.9) | 3 (8.6) | 6 (17.1) | 0.477b |
| Postoperative hospital stay, days | 17 (6–64) | 17 (8–61) | 19 (6–64) | 0.101 |
| Adjuvant chemotherapy | 54 (78.3) | 29 (82.9) | 25 (73.5) | 0.348 |
Estimated using the following formula: Total in-out balance/body weight (kg)/anesthesia time (h). Continuous variables are presented as the median (range) and were analyzed using the Mann-Whitney U-test. Categorical variables are reported as the number (percentage) and were analyzed using the χ2 test or Fisher's exact test, as appropriate.
Fisher's exact test was performed, while other comparisons for categorical variables were carried out using the χ2 test. ANH, acute normovolemic hemodilution; CBV, circulating blood volume; FFP, fresh frozen plasma; IBL, intraoperative blood loss; ISGPF, the International Study Group of Pancreatic Fistula; ISGPS, the International Study Group of Pancreatic Surgery; PC, platelet concentration; STD, standard management.