Table 4.
The susceptibility patterns of 30 CRE (10 E.coli + 20 K. pneumoniae) isolates versus all tested antimicrobial agents
| Agents | Susceptibility pattern of 30 CRE isolates; 10 E. coli + (20 K. pneumoniae) (mg/L) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| <0.06 | 0.125 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | 128 | >128 | |
| FTB | 0 | 0 + (1) | 0 | 1 + (2) | 1 + (5) | 1 + (5) | 0 + (3) | 3 + (3) | 2 + (1) | 2 + (0) | 0 | 0 | 0 |
| FEP | 0 | 0 | 0 | 0 | 0 | 0 | 0 + (1) | 0 + (1) | 0 + (1) | 0 + (1) | 0 | 3 + (3) | 7 + (13) |
| CZA | 0 | 0 | 0 + (2) | 1 + (2) | 0 + (6) | 2 + (2) | 0 + (2) | 2 + (2) | 0 + (2) | 0 | 0 + (1) | 0 | 5 + (1) |
| C/T | 0 | 0 | 0 | 0 | 2 + (0) | 0 | 3 + (1) | 1 + (1) | 2 + (8) | 1 + (5) | 1 + (3) | 0 + (1) | 0 + (1) |
| MEM | 0 | 0 | 0 | 0 | 3 + (3) | 0 + (4) | 0 + (3) | 3 + (1) | 1 + (2) | 1 + (1) | 1 + (1) | 0 + (1) | 1 + (4) |
| TZP | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 + (2) | 1 + (1) | 0 | 1 + (0) | 0 | 8 + (17) |
| LVX | 0 | 0 | 0 | 0 | 0 + (1) | 0 | 2 + (0) | 3 + (2) | 3 + (7) | 1 + (5) | >32: 1+ (5)a | ||
| AMK | 0 | 0 | 0 + (1) | 0 + (2) | 0 + (3) | 1 + (2) | 1 + (5) | 1 + (0) | 3 + (2) | 0 + (3) | 1 + (0) | 0 | 3 + (2) |
FTB, cefepime/taniborbactam; AMK, amikacin; FEP, cefepime; CZA, ceftazidime/avibactam; C/T, ceftolozane/tazobactam; MEM, meropenem; TZP, piperacillin/tazobactam; LVX, levofloxacin.
aThe concentrations of all tested antimicrobial agents ranged from 0.06 to 128 mg/L, except LVX (from 0.06 to 32 mg/L).