Table 2.

Perinatal outcomes of singleton pregnancies, focusing on babies that died

Perinatal outcomes	Whole cohort (n=326)*	Gestational age at PPROM (weeks+days)				Unadjusted relative rate ratio of outcome for each additional week of gestation at PPROM (RR (95% CI), P value)
		16+0-17+6 (n=82)	18+0-19+6 (n=102)	20+0-21+6 (n=105)	22+0-22+6 (n=37)
Termination for medical reasons without expectant management	62 (19)	25 (30)	19 (19)	17 (16)	1 (3)	0.75 (0.64 to 0.87), 0.001
Termination for medical reasons after expectant management	41 (13)	14 (17)	13 (13)	8 (8)	6 (16)	0.92 (0.77 to 1.09), 0.33
Birth or intrauterine death <22+0 weeks' gestation (miscarriage) (expectant management throughout pregnancy)	90/223 (40)	26/33 (79)	37/70 (53)	27/80 (34)	—	0.80 (0.70 to 0.91), 0.001
Intrauterine deaths ≥22+0 weeks' gestation (expectant management throughout pregnancy)	35/223 (16)	3/33 (9)	6/70 (9)	16/80 (20)	10/30 (33)	1.59 (1.27 to 1.99), 0.001
Neonatal deaths (expectant management throughout pregnancy)	28/223 (13)	4/33 (12)	8/70 (11)	10/80 (13)	6/30 (20)	1.24 (1.00 to 1.53), 0.05

Data are No (%) or No/total No (%). CI=confidence interval; PPROM=preterm prelabour rupture of membranes; RR=relative rate.

*Gestational age at PPROM 16+0-22+6 weeks+days.