Figure 3. Loss of Bcl-3 specifically in CD4+ T cells led to accumulation of RORγt+ regulatory T cells upon α-CD3 treatment.
Bcl-3F/F CD4-Cre conditional KO and control Bcl-3WT/F CD4-Cre mice were injected i.p. with CD3-specific antibody and sacrificed on day 4. (a) Representative flow cytometric analyses of cells from mesenteric lymph node. (b) Summary of flow cytometric analyses as shown in (a) (n ≥ 5 from three experiments). Data represent means ± SD.