TABLE 2.
Kaposin-transformed Rat-3 cells are tumorigenic in athymic nu/nu micea
| Expt | Cell line | PCR positive for kaposin sequence | No. of mice with tumor(s)/no. injected | Latency (wk) |
|---|---|---|---|---|
| 1 | R3/23-1 | + | 5/5 | 1 |
| R3/T0.7-1 | + | 5/5 | 1 | |
| R3/T0.7-2 | + | 4/4 | 1 | |
| R3/T0.7-3 | + | 4/4 | 1–2 | |
| R3/kap-1 | + | 5/5 | 1 | |
| R3/kap-2 | + | 3/4 | 1–2 | |
| Rat-3 | − | 0/3 | ||
| 2 | R3/kap-G1 | NT | 4/4 | 1 |
| R3/BK-G1 | NT | 0/4 |
a
Each mouse was injected subcutaneously behind the neck with 5 × 106 cells and examined twice each week. Some tumors were greater than 1 cm in diameter by 2 weeks. NT, not tested.