Fig 3. Superposed 8 native glutamate transporters and their QTY variants that were predicted by AlphaFold2.

The native structures (green) and their water-soluble QTY variants (cyan). For the superposed structures, the RMSD is in Å (). a, EAA1 vs EAA1^QTY (0.717Å), b, EAA2 vs EAA2^QTY (0.948Å), c, EAA3 vs EAA3^QTY (0.905Å), d, EAA4 vs EAA4^QTY (0.796Å), e, VGLUT1 vs VGLUT1^QTY (1.604Å), f, VGLUT2 vs VGLUT2^QTY (0.971Å), g, VGLUT3 vs VGLUT3^QTY (1.422Å), h, YLAT2 vs YLAT2^QTY (0.528Å). For clarity, N- and C- termini and large loops are deleted. Please see Tables 1 and 2.