Table 4.

Physician reports of anxiety, stress/adjustment reaction and depressive conditions by infection wave for healthcare workers (HCW) and community referents (CR)

Wave		Anxiety				Stress/adjustment reaction				Depression
		HCW	CR		All	HCW	CR		All	HCW	CR		All
1 (March–June 2020)	N	297	1431		1728	102	392		494	234	964		1198
	%	10.0	9.8		9.9	3.4	2.7		2.8	7.9	6.6		6.8
2 (July 2020–February 2021)	N	446	1950		2396	177	650		827	360	1329		1689
	%	15.1	13.4		13.7	6.0	4.5		4.7	12.2	9.1		9.6
3 (March–June 2021)	N	325	1514		1839	144	465		609	264	1011		1275
	%	11.0	10.4		10.5	4.9	3.2		3.5	8.9	7.0		7.3
4 (July–October 2021)	N	278	1245		1523	120	352		472	246	816		1062
	%	9.4	8.6		8.7	4.1	2.4		2.7	8.3	5.6		6.1
5 (November 2021–March 2022)	N	348	1524		1872	141	429		570	285	1045		1330
	%	11.8	10.5		10.7	4.8	2.9		3.3	9.6	7.2		7.6
N		2959	14,546		17,505	2959	14,546		17,505	2959	14,546		17,505
HCW risk of physician report of mental ill-health by wave
Wave		Anxiety				Stress/adjustment reaction				Depression
		Unadjusted		Adjusted*		Unadjusted		Adjusted*		Unadjusted		Adjusted*
1 (March–June 2020)	OR	1.10		1.12		1.44		1.45		1.36		1.27
	95% CI	0.90–1.34		0.92–1.36		1.09–1.90		1.11–1.91		1.06–1.75		1.00–1.61
	p-value	0.368		0.263		0.010		0.007		0.016		0.048
2 (July 2020–February 2021)	OR	1.30		1.33		1.55		1.55		1.74		1.62
	95% CI	1.09–1.56		1.12–1.58		1.23–1.95		1.24–1.94		1.40–2.16		1.31–2.00
	p-value	0.004		0.001		<0.001		<0.001		<0.001		<0.001
3 (March–June 2021)	OR	1.16		1.18		1.83		1.84		1.58		1.46
	95% CI	0.95–1.41		0.98–1.43		1.43–2.35		1.44–2.34		1.24–2.01		1.16–1.84
	p-value	0.136		0.081		<0.001		<0.001		<0.001		0.001
4 (July–October 2021)	OR	1.25		1.27		2.05		2.07		2.07		1.89
	95% CI	1.02–1.54		1.04–1.55		1.57–2.69		1.59–2.69		1.61–2.66		1.49–2.39
	p-value	0.034		0.017		<0.001		<0.001		<0.001		<0.001
5 (November 2021–March 2022)	OR	1.30		1.32		1.98		1.99		1.73		1.60
	95% CI	1.07–1.58		1.10–1.59		1.54–2.55		1.55–2.54		1.36–2.19		1.28–2.00
	p-value	0.008		0.003		<0.001		<0.001		<0.001		<0.001
N		17,505				17,505				17,505

^*Adjusted for physician report of the same condition in the 3 years before the pandemic