Table 2.
Negative binomial regression analysis results of relationships between clinical outcome measures and predictors.
| Hamilton depression rating scale–GM thickness model | 95% Wald confidence interval for Exp (B) | |||||
|---|---|---|---|---|---|---|
| p | q | B | Exp (B) | Lower | Upper | |
| L inferior temporal | ≤ 0.001 | 0.003 | − 5.64 | 0.004 | 0.00 | 0.07 |
| L pars opercularis | 0.002 | 0.01 | 4.87 | 130.22 | 5.57 | 3044.72 |
| L transverse temporal | 0.02 | 0.06 | − 2.04 | 0.13 | 0.02 | 0.69 |
| L isthmus cingulate | 0.03 | 0.09 | 2.26 | 9.56 | 1.16 | 78.45 |
| L temporal pole | 0.05 | 0.10 | − 1.09 | 0.33 | 0.11 | 0.98 |
| L pericalcarine | 0.18 | 0.34 | 2.16 | 8.67 | 0.36 | 209.17 |
| L superior frontal | 0.27 | 0.42 | 1.94 | 6.95 | 0.22 | 217.28 |
| Sex | 0.48 | 0.62 | − 0.11 | 0.89 | 0.65 | 1.22 |
| R postcentral | 0.55 | 0.62 | 1.09 | 2.97 | 0.08 | 108.25 |
| IQ | 0.59 | 0.62 | − 0.04 | 0.96 | 0.84 | 1.10 |
| Age | 0.620 | 0.62 | − 0.03 | 0.97 | 0.85 | 1.10 |
| Omnibus test (Likelihood Ratio Chi-Square = 1574,44 df = 11, p ≤ 0.001) | ||||||
| Young mania rating scale–GM thickness model | 95% Wald confidence interval for Exp (B) | |||||
|---|---|---|---|---|---|---|
| p | q | B | Exp (B) | Lower | Upper | |
| L pars opercularis | ≤ 0.001 | ≤ 0.001 | 6.08 | 439.03 | 20.58 | 9364.40 |
| L inferior temporal | ≤ 0.001 | ≤ 0.001 | − 6.47 | 0.002 | 5.65E−05 | 0.04 |
| L isthmus cingulate | 0.03 | 0.06 | 2.81 | 16.63 | 1.39 | 199.07 |
| L temporal pole | 0.07 | 0.12 | − 1.31 | 0.27 | 0.07 | 1.10 |
| Age | 0.32 | 0.44 | − 0.07 | 0.97 | 0.82 | 1.14 |
| Sex | 0.52 | 0.60 | 0.12 | 1.13 | 0.78 | 1.65 |
| IQ | 0.69 | 0.69 | − 0.03 | 0.97 | 0.82 | 1.14 |
| Omnibus test (Likelihood Ratio Chi-Square = 46.42, df = 7, p ≤ 0.001) | ||||||
| Hamilton anxiety rating scale–GM thickness model | 95% Wald confidence interval for Exp (B) | |||||
|---|---|---|---|---|---|---|
| p | q | B | Exp (B) | Lower | Upper | |
| L inferior temporal | ≤ 0.001 | ≤ 0.001 | − 6.77 | 0.00 | 6.23E−05 | 0.02 |
| L pars opercularis | 0.002 | 0.01 | 4.68 | 107.85 | 5.60 | 2075.19 |
| L isthmus cingulate | 0.01 | 0.04 | 2.84 | 17.05 | 1.93 | 150.76 |
| L temporal pole | 0.07 | 0.17 | − 1.00 | 0.37 | 0.12 | 1.09 |
| Sex | 0.09 | 0.17 | − 0.28 | 0.75 | 0.55 | 1.04 |
| L parahippocampal | 0.16 | 0.23 | 0.92 | 2.51 | 0.70 | 8.99 |
| L pericalcarine | 0.16 | 0.23 | 2.19 | 8.97 | 0.41 | 195.86 |
| R postcentral | 0.67 | 0.83 | 0.75 | 2.13 | 0.07 | 65.52 |
| Age | 0.86 | 0.86 | − 0.01 | 0.99 | 0.86 | 1.13 |
| IQ | 0.86 | 0.86 | − 0.01 | 0.99 | 0.86 | 1.13 |
| Omnibus test (Likelihood Ratio Chi-Square = 1147.48, df = 10, p ≤ 0.001) | ||||||
CI, Confidence Interval; L, left; R, right; GM, Gray matter; q, False Discovery Rate (FDR). Benjamini–Hochberg FDR corrected adjusted p-value < .05. Exp (B) = odds ratio or a 1 unit change in predictor variable is an Exp (B) increase in the dependent variable (depression score).
Significant p-values in italics, FDR-corrected q in bold.